Search found 119 matches

by wuffy68
Sun Jul 10, 2022 2:51 am
Forum: Discussions of General-FAH topics
Topic: DCN future in light of (gradual) PCoIP gaming adoption
Replies: 1
Views: 226

DCN future in light of (gradual) PCoIP gaming adoption

Forward looking question that's probably been answered somewhere. With the gradual adoption of PCoIP/cloud gaming, how do DCNs plan on migrating from an at-home model to one that requires a subscription service to a cloud data center. People may be willing to pay-to-play games ... But paying to fold...
by wuffy68
Sat Jul 09, 2022 7:44 pm
Forum: The Science of FAH -- questions/answers
Topic: Powassan virus (POWV)
Replies: 2
Views: 213

Re: Powassan virus (POWV)

it would be amazing if any findings from Dengue could be extended to POWV...
by wuffy68
Thu Jul 07, 2022 7:29 am
Forum: The Science of FAH -- questions/answers
Topic: Powassan virus (POWV)
Replies: 2
Views: 213

Powassan virus (POWV)

Medical news has been spreading on social media about the emerging concerns over the Powassan flavivirus (POWV) ... a tick-borne disease that can have long-term debilitating consequences for its victims (perhaps worse than Lyme disease - which is a Rotavirus). Even in recovered patients, symptoms ca...
by wuffy68
Sat May 07, 2022 7:56 pm
Forum: The Science of FAH -- questions/answers
Topic: Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations
Replies: 0
Views: 326

Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

Recently, I was watching a 2020 Tedx talk by Dr. Christal Sohl (of San Diego State University) that mentioned recent drug discoveries related to IDH and cancer therapeutics. My best guess is, she was talking about Eli Lilly's IDH1/2 Inhibitor LY3410738 (but the talk doesn't mention the company or dr...
by wuffy68
Sat Oct 16, 2021 7:04 am
Forum: V7.6.x Public Release Windows/Linux/MacOS X
Topic: New API statistics - based on passkey query
Replies: 5
Views: 3804

Re: New API statistics - based on passkey query

Just a hunch, they might be using a passkey with a variety of usernames. ... this is for a club-within-a-team user account ... We want to track individual contributions to a single user account, to see if they've submitted at least 10 WU's to earn the bonus PPD for the main user account - proving t...
by wuffy68
Sat Oct 16, 2021 6:49 am
Forum: V7.6.x Public Release Windows/Linux/MacOS X
Topic: New API statistics - based on passkey query
Replies: 5
Views: 3804

Re: New API statistics - based on passkey query

curl -G https://api.foldingathome.org/user/name -d passkey=<string> curl -G https://api.foldingathome.org/user/name/stats -d passkey=<string> curl -G https://api.foldingathome.org/bonus -d user=<string> -d passkey=<string> Thank you! I finally broke down and installed curl (was using http requests ...
by wuffy68
Sun Sep 26, 2021 5:24 pm
Forum: V7.6.x Public Release Windows/Linux/MacOS X
Topic: New API statistics - based on passkey query
Replies: 5
Views: 3804

New API statistics - based on passkey query

Hey Community ... in the past, we were able to get statistics by passkey using the following api query: https://stats.foldingathome.org/api/donors?passkey=<passkey> Since this is no longer available, is there a way to get passkey-specific queries using the new api query: https://api2.foldingathome.o...
by wuffy68
Tue Jul 06, 2021 1:23 am
Forum: The Science of FAH -- questions/answers
Topic: Long Term Roadmap?
Replies: 5
Views: 13194

Re: Long Term Roadmap?

There are actually 3 different versions and the rules change for each. F@H works with some but others were particularly difficult to code for. Interesting ... what is the range of performance one can expect (best, worst, average - given an identical WU), and are there BIOS-level settings that would...
by wuffy68
Mon Jul 05, 2021 11:29 pm
Forum: The Science of FAH -- questions/answers
Topic: Long Term Roadmap?
Replies: 5
Views: 13194

Re: Long Term Roadmap?

The researchers posted something like this, but it's 9 years old: https://folding.typepad.com/news/2012/0 ... -come.html Thank you - that would be a good basis to build upon starting in 2021 (along with adding a little more sci-fi factor for projections farther out). Unfortunately "villin"...
by wuffy68
Mon Jul 05, 2021 8:04 pm
Forum: The Science of FAH -- questions/answers
Topic: Long Term Roadmap?
Replies: 5
Views: 13194

Long Term Roadmap?

The other day I posted about homunculi in-silico and the hypothetical scenario of simulating every protein in the human body simultaneously. While this may be far-out, and elicit zero response, I thought I'd focus on my final question in the post regarding long-term roadmaps. Given the current trend...
by wuffy68
Sat Jul 03, 2021 5:17 pm
Forum: The Science of FAH -- questions/answers
Topic: Future of Folding ... Homunculi?
Replies: 0
Views: 5732

Future of Folding ... Homunculi?

If you've ever seen presentations of (~in-vivo) Human Organs-on-Chips https://vimeo.com/116674365 from Wyss Institute - it brings up interesting future prospects in-silico... One can see Human Organs-On-Chips (a form of homunculus (homunculi?)) to be a realistic in-silico simulation target for distr...
by wuffy68
Wed May 05, 2021 8:17 am
Forum: The Science of FAH -- questions/answers
Topic: Silicon based life (simulated in-silico?)
Replies: 0
Views: 6828

Silicon based life (simulated in-silico?)

The results of the Urey-Miller Nanoreactor simulation from seven years ago were fascinating (with over 600 new molecular compounds found): https://youtu.be/zNHzVasizoo Was there ever any consideration of running the same experiment using silicon based reactions? There's been a lot of debate whether ...
by wuffy68
Sun Apr 11, 2021 9:53 am
Forum: Discussions of General-FAH topics
Topic: Permission to re-use the "Even while you sleep" video
Replies: 24
Views: 16246

Re: Permission to re-use the "Even while you sleep" video

It looks like my team wont be entrusted with the original video, so I'll just post the content of a hand carved .srt file with a direct transcription from the video's text content. I tried to keep the text and pacing as close to original as possible, but the timing may need to be adjusted further us...
by wuffy68
Thu Apr 08, 2021 12:58 am
Forum: Discussions of General-FAH topics
Topic: Permission to re-use the "Even while you sleep" video
Replies: 24
Views: 16246

Re: Permission to re-use the "Even while you sleep" video

I think with "Bazillion" they were going for a quintillion vibe? Maybe? I think you're right that its higher than my initial stab in the dark, but the number of actual proteins maybe lower than a quintillion (could be totally wrong since I got tired of searching for a definitive answer) I...
by wuffy68
Wed Apr 07, 2021 6:41 pm
Forum: Discussions of General-FAH topics
Topic: Permission to re-use the "Even while you sleep" video
Replies: 24
Views: 16246

Re: Permission to re-use the "Even while you sleep" video

If we're provided, say, an .srt-file with the English captions, it should be easy to translate it. Yup, that's what I plan to do in addition to fixing the URL at the end of the video - although rather than translating the text verbatim in the transcript, I plan on using more formal English in the t...